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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakata, Tsuneari | LF | Green Bay Golden Eagles | 29 | 05/29/2020 | Fukuyama | JPN | Left | Right | 6' 1" | 200 lbs | - |
| Sakurai, Masami | 3B | Saugatuck Joes | 22 | 05/16/2027 | Kakamigahara | JPN | Right | Right | 5' 11" | 175 lbs | - |
| Sawyer, Coy | RF | Free Agent | 24 | 10/14/2024 | Milwaukee | USA | Right | Right | 6' 2" | 195 lbs | - |
| Schaeffer, Ray | RP | Pointe Pelee Monarchs | 32 | 06/01/2017 | Holland | CAN | Right | Right | 6' 2" | 200 lbs | $507,500 |
| Seldon, Jon | C | Pointe Pelee Monarchs | 20 | 06/13/2029 | Walbridge | USA | Right | Right | 6' 0" | 185 lbs | - |
| Sellars, Billy | C | Saugatuck Joes | 27 | 09/18/2021 | Thunder Bay | CAN | Switch | Right | 6' 1" | 200 lbs | - |
| Serrano, Bill | C | Bay City Rollers | 24 | 07/31/2024 | Mississauga | CAN | Switch | Right | 6' 1" | 200 lbs | $507,500 |
| Sharpe, Lee | 1B | Pointe Pelee Monarchs | 25 | 06/02/2024 | Hamilton | CAN | Left | Right | 6' 5" | 215 lbs | $507,500 |
| Sherman, Joe | SP | Free Agent | 29 | 11/18/2019 | Iowa City | USA | Left | Right | 6' 5" | 195 lbs | - |
| Shewman, Mitchell | SP | Free Agent | 28 | 02/06/2021 | Holland | CAN | Right | Right | 6' 7" | 205 lbs | - |
| Silva, Bartolo | CF | London Eclipse | 28 | 11/23/2020 | Marcala | HON | Right | Right | 6' 6" | 200 lbs | - |
| Simmons, Robby | 1B | Green Bay Golden Eagles | 29 | 01/18/2020 | Wauwatosa | USA | Left | Left | 6' 4" | 200 lbs | - |
| Simon, Brent | RP | London Eclipse | 37 | 12/28/2011 | Ventura | USA | Right | Right | 6' 4" | 200 lbs | $3,200,000 |
| Simon, Valentin | RP | Mississauga Mad Catz | 26 | 06/17/2023 | London | CAN | Right | Right | 6' 0" | 190 lbs | - |
| Skeffington, Patrick | 1B | London Eclipse | 22 | 09/23/2026 | St. Paul | USA | Right | Right | 6' 3" | 200 lbs | - |
| Smith, Bob | SP | Mississauga Mad Catz | 21 | 11/12/2027 | Cleveland | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Kurt | RF | Harbor Springs Expedition | 22 | 02/24/2027 | Thiensville | USA | Left | Left | 6' 2" | 200 lbs | - |
| Springer, Xavier | 2B | Mississauga Mad Catz | 27 | 02/14/2022 | Boardman | USA | Right | Right | 5' 9" | 195 lbs | - |
| Stanford, John | RF | Mackinac Island Cougars | 25 | 10/23/2023 | Caledonia | USA | Left | Left | 6' 3" | 200 lbs | $507,500 |
| Starr, Darryl | RP | Manitoulin Island Royals | 29 | 12/07/2019 | Holland | CAN | Right | Right | 6' 2" | 200 lbs | $507,500 |
| Stenissen, Noah | 1B | Leamington Mariners | 27 | 08/12/2021 | s-Hertogenbosch | NED | Right | Right | 6' 2" | 210 lbs | - |
| Stewart, Dan | 1B | Mackinac Island Cougars | 25 | 03/30/2024 | Midland | USA | Right | Right | 5' 9" | 180 lbs | $507,500 |
| Stokes, Scott | 3B | Free Agent | 30 | 10/27/2018 | Holland | CAN | Right | Right | 5' 10" | 185 lbs | - |
| Stott, Bill | SP | London Eclipse | 26 | 05/27/2023 | Oshawa | CAN | Right | Right | 5' 11" | 195 lbs | - |
| Stott, Larry | RP | Saugatuck Joes | 21 | 09/07/2027 | London | CAN | Right | Right | 6' 2" | 190 lbs | $507,500 |
| Sulis, Gavin | RF | Bay of Quinte Herons | 27 | 08/08/2021 | Nanticoke | CAN | Right | Right | 6' 4" | 220 lbs | - |
| Sullivan, Dave | 2B | Mississauga Mad Catz | 27 | 01/21/2022 | London | CAN | Right | Right | 6' 0" | 195 lbs | - |
| Sweet, Arlen | CL | Bay City Rollers | 25 | 08/30/2023 | Lincoln | USA | Right | Right | 5' 10" | 180 lbs | $507,500 |
| Sweetland, Flynn | 3B | Bay City Rollers | 22 | 04/11/2027 | Toronto | CAN | Right | Right | 6' 3" | 195 lbs | - |
| Sykes, Davey | RP | Saugatuck Joes | 24 | 12/03/2024 | Akron | USA | Right | Left | 6' 1" | 200 lbs | - |
| Sánchez, Carlos | CF | Leamington Mariners | 25 | 12/17/2023 | Miamisburg | USA | Switch | Right | 6' 0" | 205 lbs | - |
