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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dale O'Brien | 2015-2024 | 108 | 64 | .628 | 2.71 | 261 | 242 | 12 | 6 | 0 | 1557.0 | 1375 | 469 | 142 | 194 | 1117 |
| Larry O'Connell | 2042-2048 | 22 | 16 | .579 | 3.04 | 272 | 4 | 0 | 0 | 14 | 319.1 | 281 | 108 | 16 | 98 | 177 |
| David O'Neil | 2033-2035 | 0 | 1 | .000 | 5.52 | 11 | 0 | 0 | 0 | 0 | 14.2 | 21 | 9 | 9 | 6 | 13 |
| Arnold O'Sullivan | 2042-2045 | 9 | 16 | .360 | 5.22 | 171 | 1 | 0 | 0 | 3 | 246.1 | 257 | 143 | 15 | 184 | 119 |
| Josh O'Toole | 2030-2038 | 45 | 32 | .584 | 3.69 | 127 | 123 | 3 | 3 | 0 | 714.1 | 641 | 293 | 67 | 253 | 540 |
| Mike O'Toole | 2037-2042 | 5 | 1 | .833 | 4.05 | 139 | 0 | 0 | 0 | 0 | 211.1 | 210 | 95 | 25 | 76 | 159 |
| Jeff O'Vesy | 2015-2021 | 20 | 18 | .526 | 2.55 | 387 | 0 | 0 | 0 | 56 | 413.0 | 309 | 117 | 18 | 113 | 466 |
| Hirofumi Oike | 2026-2026 | 0 | 1 | .000 | 4.50 | 1 | 1 | 0 | 0 | 0 | 4.0 | 4 | 2 | 0 | 3 | 4 |
| Pablo Ojeda | 2040-2048 | 72 | 91 | .442 | 3.22 | 228 | 227 | 1 | 0 | 0 | 1427.0 | 1266 | 510 | 80 | 596 | 858 |
| Chris Oldford | 2017-2018 | 2 | 4 | .333 | 2.64 | 62 | 0 | 0 | 0 | 2 | 44.1 | 31 | 13 | 4 | 16 | 37 |
| Charles Olivares | 2020-2030 | 21 | 14 | .600 | 3.58 | 354 | 0 | 0 | 0 | 14 | 360.0 | 336 | 143 | 31 | 138 | 226 |
| Ron Oliver | 2022-2023 | 1 | 1 | .500 | 5.12 | 28 | 0 | 0 | 0 | 0 | 38.2 | 44 | 22 | 4 | 18 | 33 |
| Tom Oliver | 2047-2048 | 3 | 9 | .250 | 6.02 | 36 | 15 | 0 | 0 | 0 | 101.2 | 115 | 68 | 20 | 56 | 74 |
| Simon Olivier | 2046-2048 | 15 | 3 | .833 | 2.38 | 80 | 0 | 0 | 0 | 1 | 113.2 | 93 | 30 | 8 | 38 | 102 |
| César Olvera | 2034-2035 | 0 | 1 | .000 | 5.10 | 36 | 0 | 0 | 0 | 0 | 47.2 | 58 | 27 | 8 | 19 | 41 |
| Javier Orozco | 2025-2031 | 20 | 18 | .526 | 4.92 | 241 | 11 | 0 | 0 | 2 | 369.1 | 383 | 202 | 70 | 147 | 327 |
| Octávio Orozco | 2015-2023 | 0 | 0 | .000 | 40.50 | 1 | 0 | 0 | 0 | 0 | 0.2 | 3 | 3 | 0 | 1 | 1 |
| Gary Orr | 2026-2026 | 1 | 3 | .250 | 9.90 | 23 | 0 | 0 | 0 | 0 | 10.0 | 11 | 11 | 2 | 6 | 2 |
| Nessun Orrell | 2017-2022 | 7 | 4 | .636 | 4.09 | 48 | 9 | 2 | 1 | 0 | 112.1 | 125 | 51 | 11 | 33 | 57 |
| Leonard Ortíz | 2019-2025 | 39 | 44 | .470 | 3.37 | 121 | 120 | 7 | 2 | 0 | 732.1 | 679 | 274 | 57 | 224 | 593 |
| Manuel Ortíz | 2037-2040 | 3 | 3 | .500 | 3.58 | 54 | 2 | 0 | 0 | 0 | 93.0 | 87 | 37 | 12 | 24 | 62 |
| Silas Osborne | 2030-2042 | 70 | 92 | .432 | 3.94 | 265 | 225 | 14 | 7 | 1 | 1447.0 | 1380 | 633 | 178 | 470 | 986 |
| Kelvin Ouwens | 2024-2031 | 38 | 45 | .458 | 4.45 | 271 | 131 | 0 | 0 | 2 | 843.1 | 1003 | 417 | 99 | 212 | 416 |
